Almost 50% of the ESCAPE Network partners are also members of ERKNet, the European Reference Network for Rare Kidney Diseases. This EU funded Network is dedicated to improving the care of patients with rare kidney disorders by providing virtual consultations, developing, implementing and monitoring the impact of clinical practice guidelines, promoting education and training of rare kidney disease specialists - and by fostering clinical research. The ESCAPE Network is instrumental in materializing clinical trials in children with rare kidney diseases.

ESCAPE is closely associated with c4c (conect4children), the Pan-european Clinical Trial Network for Children (Conect4Children). Several ESCAPE Network members participate as experts in the c4c Expert Advisory Group for drug development programs in pediatric nephrology and hypertension. The c4c project receives public-private co-funding from the EU and EFPIA as part of the Innovative Medicines Initiative(IMI).

The ESCAPE Network researchers are also active members of the European Society for Paediatric Nephrology (ESPN). The Society's expert working groups are in close exchange with the ESCAPE Network, generating ideas for relevant clinical research. Moreover, the ESPN is an important sponsor of research projects of the Network through its Research Grant Programme.

The CKiD consortium is following a large cohort of North American children with chronic kidney disease. The similar designs of the CKiD cohort and the 4C Study and ESCAPE Trial cohorts followed by the ESCAPE Network is providing a wealth of opportunities for transatlantic collaboration, which have resulted in important joint projects and publications. Some of the collaborative activities have been co-funded by the NIH.